Fluoroquinolones

. Posted in TREATING SINUS DISEASE

Fluoroquinolones (also known as quinolones) prevent bacteria from multiplying because they interfere with the bacteria’s genetic material. The first quinolone used was ciprofloxacin (Cipro). Since that time other quinolones were developed, including levofloxacin (Levaquin), gemifloxacin (Factive), moxifloxacin (Avelox), and ofloxacin (Floxin). The newer fluoroquinolones are currently the most effective agents against the common bacteria that cause sinusitis. Levofloxacin was the first drug approved specifically for penicillin - resistant Streptococcus pneumoniae, although studies are now finding resistance to this agent as well. These agents are recommended for adults with moderate sinusitis who have already been treated with antibiotics within 6 weeks or who are allergic to beta-lactam antibiotics.

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